Withaferin A
Product Description
Withaferin A is a steroidal lactone, derived from Acnistus arborescens, Withania somnifera (Indian Winter cherry or Bharatiya Ashwagandha in Sanskrit) and other members of family Solanaceae. It has been traditionally used in ayurvedic medicine. It is the first member of the withanolide class of ergostane type product to be discovered. This natural product has wide range of pharmacological activities including cardioprotective, anti-inflammatory, immuno-modulatory, anti-angiogenesis,anti-metastasis and anti-carcinogenic properties.
Description of Withaferin A
- Commodity Name: Withaferin A
- Item No. : URM-3603
- Product Specification: 20%/98%
- Product Name: Withaferin A
- Product Appearance: White powder
- Detection Method: HPLC
- Store: In a cool,dark and dry place protected from direct source of heat and sunlight.
- CAS No.: 5119-48-2
- Packing: 1kg in one alu. foil bag
- Molecular Formula: C28H38O6
- Molecular Weight: 470.61
- Shelf Life: 24 months
Applications of Withaferin A
Withaferin A is a bioactive compound derived from the plant Withania somnifera, commonly known as ashwagandha. It is a steroidal lactone and part of a class of compounds known as withanolides. Withaferin A has been studied for its diverse range of biological activities, including:
- Anti-inflammatory: Withaferin A has been shown to inhibit various inflammatory pathways, making it a potential treatment for inflammatory diseases.
- Anticancer: It exhibits cytotoxic effects on a variety of cancer cell lines by inducing apoptosis (programmed cell death), inhibiting angiogenesis (formation of new blood vessels that feed tumors), and interfering with the cell cycle.
- Antioxidant: It helps in reducing oxidative stress by neutralizing free radicals and enhancing the body’s own antioxidant defense mechanisms.
- Neuroprotective: Withaferin A has potential benefits in protecting against neurodegenerative diseases by reducing inflammation and oxidative stress in the nervous system.
- Immunomodulatory: It can modulate the immune system, enhancing the body’s ability to fight infections and possibly reducing autoimmune reactions.
- Anti-microbial: Withaferin A shows activity against various microbes, including bacteria and fungi, making it a potential agent for treating infections.
