Psoralen
Product Description
Psoralen is an active pharmaceutical ingredient, extracted from the seeds of psoralea corylifolia.
Description of Psoralen
- Commodity Name: Psoralen
- Item No. : URM-0067
- Product Specification: 40%/98%
- Product Appearance: Off-whiteto white powder
- Detection Method: HPLC
- Store: In a cool,dark and dry place protected from direct source of heat and sunlight.
- CAS No.: 66-97-7
- Packing: 1kg in one alu.foil bag
- Molecular Formula: C11H6O3
- Molecular Weight: 186.16354
- Shelf Life: 24 months
Application of Psoralen
Psoralen’s Role in Vitiligo Treatment
- Mechanism of Action: Psoralen works by making the skin more sensitive to ultraviolet (UV) light. When combined with UVA light exposure (a treatment known as PUVA therapy), psoralen can help stimulate melanocyte activity, the cells responsible for producing pigment in the skin. This can potentially lead to the repigmentation of the white patches seen in vitiligo.
- PUVA Therapy: PUVA therapy involves the oral or topical application of psoralen followed by controlled exposure to UVA light. This treatment can help in repigmenting the skin over time. It is one of the more established treatments for vitiligo, though it requires careful monitoring and administration by a healthcare professional due to potential side effects, such as skin irritation, burning, and an increased risk of skin cancer with long-term use.
- Effectiveness: The effectiveness of PUVA therapy can vary from person to person. Some patients experience significant repigmentation, while others may see minimal improvement. The therapy often requires multiple sessions over an extended period to achieve desired results.
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Related News
Psoralen is a naturally occurring compound found in several plants, including the Babchi plant (Psoralea corylifolia), and has been recognized […]
